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Esse mapa conceitual, produzido no IHMC CmapTools, tem a informação relacionada a: G6PD Def. Added genetic piece, Pentose Phosphate Pathway is regulated by the levels of NADPH, Reticulocyte Count 262 x 10^9/L contribute to diagnosis of deficiency of G6PD, Rigidity and Fragility of RBCs Are removed by Macrophages, NADPH/NADP ratio when high inhibits G6PD, reduced Glutathione (GSH) used by glucathione peroxidase, Anemia contribute to diagnosis of deficiency of G6PD, erythropoiesis leads to increased Reticulocyte Count 262 x 10^9/L, Patient in Case 1 50 y/o Female Presents w/ Total Serum Bilirubin 19 mg/dL, hemoglobin Loss of which causes Decreased Oxygen binding capacity, Pentose Phosphate Pathway when active increases NADPH/NADP ratio, hemoglobin when denatured and oxidized intracellularly is seen microscopically as Heinz bodies, lyonization results from deactivation of one x chromosome, Biliverden is reduced to Unconjugated Bilirubin, NADPH is needed by glucothione reductase, Heinz bodies bind to membranes of RBCs, NADP to NADPH, Indirect Bilirubin contributing to Total Serum Bilirubin 19 mg/dL, X Chromosome at the q28 locus, X-linked recessive inheritance characterized in females by lyonization, NADPH Deficiency in RBCs